GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose

Overeating and arrhythmic feeding promote obesity and diabetes. Glucagon-like peptide-1 receptor (GLP-1R) agonists are effective anti-obesity drugs but their use is limited by side effects. Here we show that oral administration of the non-calorie sweetener, rare sugar d-allulose (d-psicose), induces...

Descripción completa

Detalles Bibliográficos
Autores principales: Iwasaki, Yusaku, Sendo, Mio, Dezaki, Katsuya, Hira, Tohru, Sato, Takehiro, Nakata, Masanori, Goswami, Chayon, Aoki, Ryohei, Arai, Takeshi, Kumari, Parmila, Hayakawa, Masaki, Masuda, Chiaki, Okada, Takashi, Hara, Hiroshi, Drucker, Daniel J., Yamada, Yuichiro, Tokuda, Masaaki, Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760716/
https://www.ncbi.nlm.nih.gov/pubmed/29317623
http://dx.doi.org/10.1038/s41467-017-02488-y

Ejemplares similares

Ejemplares similares