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Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography

A simple and reliable high performance liquid chromatography (HPLC) method has been developed for the simultaneous quantification of five major bioactive components in ‘Shu-Jin-Zhi-Tong’ capsules (SJZTC), for the purposes of quality control of this commonly prescribed traditional Chinese medicine. U...

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Detalles Bibliográficos
Autores principales: Yang, Xing-Xin, Zhang, Xiao-Xia, Chang, Rui-Miao, Wang, Yan-Wei, Li, Xiao-Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760797/
https://www.ncbi.nlm.nih.gov/pubmed/29403711
http://dx.doi.org/10.1016/j.jpha.2011.08.002
Descripción
Sumario:A simple and reliable high performance liquid chromatography (HPLC) method has been developed for the simultaneous quantification of five major bioactive components in ‘Shu-Jin-Zhi-Tong’ capsules (SJZTC), for the purposes of quality control of this commonly prescribed traditional Chinese medicine. Under the optimum conditions, excellent separation was achieved, and the assay was fully validated in terms of linearity, precision, repeatability, stability and accuracy. The validated method was applied successfully to the determination of the five compounds in SJZTC samples from different production batches. The HPLC method can be used as a valid analytical method to evaluate the intrinsic quality of SJZTC.