Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography

A simple and reliable high performance liquid chromatography (HPLC) method has been developed for the simultaneous quantification of five major bioactive components in ‘Shu-Jin-Zhi-Tong’ capsules (SJZTC), for the purposes of quality control of this commonly prescribed traditional Chinese medicine. U...

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Detalles Bibliográficos
Autores principales: Yang, Xing-Xin, Zhang, Xiao-Xia, Chang, Rui-Miao, Wang, Yan-Wei, Li, Xiao-Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760797/
https://www.ncbi.nlm.nih.gov/pubmed/29403711
http://dx.doi.org/10.1016/j.jpha.2011.08.002
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author Yang, Xing-Xin
Zhang, Xiao-Xia
Chang, Rui-Miao
Wang, Yan-Wei
Li, Xiao-Ni
author_facet Yang, Xing-Xin
Zhang, Xiao-Xia
Chang, Rui-Miao
Wang, Yan-Wei
Li, Xiao-Ni
author_sort Yang, Xing-Xin
collection PubMed
description A simple and reliable high performance liquid chromatography (HPLC) method has been developed for the simultaneous quantification of five major bioactive components in ‘Shu-Jin-Zhi-Tong’ capsules (SJZTC), for the purposes of quality control of this commonly prescribed traditional Chinese medicine. Under the optimum conditions, excellent separation was achieved, and the assay was fully validated in terms of linearity, precision, repeatability, stability and accuracy. The validated method was applied successfully to the determination of the five compounds in SJZTC samples from different production batches. The HPLC method can be used as a valid analytical method to evaluate the intrinsic quality of SJZTC.
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spelling pubmed-57607972018-02-05 Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography Yang, Xing-Xin Zhang, Xiao-Xia Chang, Rui-Miao Wang, Yan-Wei Li, Xiao-Ni J Pharm Anal Article A simple and reliable high performance liquid chromatography (HPLC) method has been developed for the simultaneous quantification of five major bioactive components in ‘Shu-Jin-Zhi-Tong’ capsules (SJZTC), for the purposes of quality control of this commonly prescribed traditional Chinese medicine. Under the optimum conditions, excellent separation was achieved, and the assay was fully validated in terms of linearity, precision, repeatability, stability and accuracy. The validated method was applied successfully to the determination of the five compounds in SJZTC samples from different production batches. The HPLC method can be used as a valid analytical method to evaluate the intrinsic quality of SJZTC. Xi'an Jiaotong University 2011-11 2011-10-22 /pmc/articles/PMC5760797/ /pubmed/29403711 http://dx.doi.org/10.1016/j.jpha.2011.08.002 Text en © 2011 Xi'an Jiaotong University http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Yang, Xing-Xin
Zhang, Xiao-Xia
Chang, Rui-Miao
Wang, Yan-Wei
Li, Xiao-Ni
Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography
title Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography
title_full Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography
title_fullStr Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography
title_full_unstemmed Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography
title_short Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography
title_sort simultaneous quantification of five major active components in capsules of the traditional chinese medicine ‘shu-jin-zhi-tong’ by high performance liquid chromatography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760797/
https://www.ncbi.nlm.nih.gov/pubmed/29403711
http://dx.doi.org/10.1016/j.jpha.2011.08.002
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