Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n)

Millettia nitida var. hirsutissima is a Chinese herbal medicine used for the treatment of gynecological diseases. An HPLC/DAD/ESI-MS(n) method was established for the rapid separation and characterization of bioactive flavonoids in M. nitida var. hirsutissima. A total of 32 flavonoids were detected,...

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Detalles Bibliográficos
Autores principales: Ye, Min, Yang, Wen-Zhi, Liu, Ke-Di, Qiao, Xue, Li, Bei-Jia, Cheng, Jun, Feng, Jie, Guo, De-An, Zhao, Yu-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760832/
https://www.ncbi.nlm.nih.gov/pubmed/29403718
http://dx.doi.org/10.1016/j.jpha.2011.09.009
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author Ye, Min
Yang, Wen-Zhi
Liu, Ke-Di
Qiao, Xue
Li, Bei-Jia
Cheng, Jun
Feng, Jie
Guo, De-An
Zhao, Yu-Ying
author_facet Ye, Min
Yang, Wen-Zhi
Liu, Ke-Di
Qiao, Xue
Li, Bei-Jia
Cheng, Jun
Feng, Jie
Guo, De-An
Zhao, Yu-Ying
author_sort Ye, Min
collection PubMed
description Millettia nitida var. hirsutissima is a Chinese herbal medicine used for the treatment of gynecological diseases. An HPLC/DAD/ESI-MS(n) method was established for the rapid separation and characterization of bioactive flavonoids in M. nitida var. hirsutissima. A total of 32 flavonoids were detected, of which 14 compounds were unambiguously characterized by comparing their retention time, UV, and MS spectra with those of the reference standards, and the others were tentatively identified based on their tandem mass spectrometry fragmentation data obtained in the negative ionization mode on line. Nineteen of these compounds characterized were reported from this plant for the first time.
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spelling pubmed-57608322018-02-05 Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n) Ye, Min Yang, Wen-Zhi Liu, Ke-Di Qiao, Xue Li, Bei-Jia Cheng, Jun Feng, Jie Guo, De-An Zhao, Yu-Ying J Pharm Anal Article Millettia nitida var. hirsutissima is a Chinese herbal medicine used for the treatment of gynecological diseases. An HPLC/DAD/ESI-MS(n) method was established for the rapid separation and characterization of bioactive flavonoids in M. nitida var. hirsutissima. A total of 32 flavonoids were detected, of which 14 compounds were unambiguously characterized by comparing their retention time, UV, and MS spectra with those of the reference standards, and the others were tentatively identified based on their tandem mass spectrometry fragmentation data obtained in the negative ionization mode on line. Nineteen of these compounds characterized were reported from this plant for the first time. Xi'an Jiaotong University 2012-02 2011-10-26 /pmc/articles/PMC5760832/ /pubmed/29403718 http://dx.doi.org/10.1016/j.jpha.2011.09.009 Text en © 2011 Xi'an Jiaotong University http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Ye, Min
Yang, Wen-Zhi
Liu, Ke-Di
Qiao, Xue
Li, Bei-Jia
Cheng, Jun
Feng, Jie
Guo, De-An
Zhao, Yu-Ying
Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n)
title Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n)
title_full Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n)
title_fullStr Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n)
title_full_unstemmed Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n)
title_short Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MS(n)
title_sort characterization of flavonoids in millettia nitida var. hirsutissima by hplc/dad/esi-ms(n)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760832/
https://www.ncbi.nlm.nih.gov/pubmed/29403718
http://dx.doi.org/10.1016/j.jpha.2011.09.009
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