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Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy
A 15-year-old boy presented to us with a 4-month history of fever with worsening dyspnea since 1 month. His contrast-enhanced computed tomography scan of the thorax showed bilateral endobronchial lesions with complete collapse-consolidation of the left lung and partial collapse of the right lower lo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760873/ https://www.ncbi.nlm.nih.gov/pubmed/29319039 http://dx.doi.org/10.4103/0970-2113.221727 |
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author | Sawant, Abhijeet Dharmaji Patil, Vijayraj S Gugalia, Pranjal M Kumar, Rajiv Jiwnani, Sabita Karimundackal, George Pramesh, CS |
author_facet | Sawant, Abhijeet Dharmaji Patil, Vijayraj S Gugalia, Pranjal M Kumar, Rajiv Jiwnani, Sabita Karimundackal, George Pramesh, CS |
author_sort | Sawant, Abhijeet Dharmaji |
collection | PubMed |
description | A 15-year-old boy presented to us with a 4-month history of fever with worsening dyspnea since 1 month. His contrast-enhanced computed tomography scan of the thorax showed bilateral endobronchial lesions with complete collapse-consolidation of the left lung and partial collapse of the right lower lobe. His fiberoptic bronchoscopy guided biopsy had been reported in outside hospital as a neuroendocrine tumor. Due to worsening breathlessness, he had to be intubated. We repeated the endobronchial biopsy and combined with outside slides and blocks, was diagnosed to have an anaplastic lymphoma kinase-1 positive anaplastic large cell lymphoma (ALCL). We started the patient on chemotherapy to which he had a dramatic response radiologically and clinically. ALCL presenting as endobronchial mass is an extremely rare occurrence and it presenting with bilateral endobronchial masses has not been reported yet in literature. Pathologists and clinicians should be aware of this presentation as prompt diagnosis and treatment give promising results. |
format | Online Article Text |
id | pubmed-5760873 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-57608732018-02-07 Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy Sawant, Abhijeet Dharmaji Patil, Vijayraj S Gugalia, Pranjal M Kumar, Rajiv Jiwnani, Sabita Karimundackal, George Pramesh, CS Lung India Case Report A 15-year-old boy presented to us with a 4-month history of fever with worsening dyspnea since 1 month. His contrast-enhanced computed tomography scan of the thorax showed bilateral endobronchial lesions with complete collapse-consolidation of the left lung and partial collapse of the right lower lobe. His fiberoptic bronchoscopy guided biopsy had been reported in outside hospital as a neuroendocrine tumor. Due to worsening breathlessness, he had to be intubated. We repeated the endobronchial biopsy and combined with outside slides and blocks, was diagnosed to have an anaplastic lymphoma kinase-1 positive anaplastic large cell lymphoma (ALCL). We started the patient on chemotherapy to which he had a dramatic response radiologically and clinically. ALCL presenting as endobronchial mass is an extremely rare occurrence and it presenting with bilateral endobronchial masses has not been reported yet in literature. Pathologists and clinicians should be aware of this presentation as prompt diagnosis and treatment give promising results. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5760873/ /pubmed/29319039 http://dx.doi.org/10.4103/0970-2113.221727 Text en Copyright: © 2017 Indian Chest Society http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Sawant, Abhijeet Dharmaji Patil, Vijayraj S Gugalia, Pranjal M Kumar, Rajiv Jiwnani, Sabita Karimundackal, George Pramesh, CS Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy |
title | Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy |
title_full | Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy |
title_fullStr | Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy |
title_full_unstemmed | Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy |
title_short | Anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy |
title_sort | anaplastic large cell lymphoma presenting as bilateral endobronchial tumor in a young boy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760873/ https://www.ncbi.nlm.nih.gov/pubmed/29319039 http://dx.doi.org/10.4103/0970-2113.221727 |
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