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Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management

Pulmonary mucormycosis is a life-threatening opportunistic fungal infection. It is considered as a disease of immunocompromised state and is rarely seen in immunocompetent patients. We here report a case of refractory bronchovascular pleuropulmonary mucormycosis, who despite early detection, optimal...

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Detalles Bibliográficos
Autores principales: Manjunath, M, Prajapat, Deepak, Sharma, Rahul Kumar, Talwar, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760874/
https://www.ncbi.nlm.nih.gov/pubmed/29319040
http://dx.doi.org/10.4103/lungindia.lungindia_535_16
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author Manjunath, M
Prajapat, Deepak
Sharma, Rahul Kumar
Talwar, Deepak
author_facet Manjunath, M
Prajapat, Deepak
Sharma, Rahul Kumar
Talwar, Deepak
author_sort Manjunath, M
collection PubMed
description Pulmonary mucormycosis is a life-threatening opportunistic fungal infection. It is considered as a disease of immunocompromised state and is rarely seen in immunocompetent patients. We here report a case of refractory bronchovascular pleuropulmonary mucormycosis, who despite early detection, optimal management with liposomal amphotericin B, and posaconazole therapy followed by surgery, progressed further and led to a fatal outcome. Dual antifungal therapy combined with surgery is the only definitive treatment option available in the literature. Many new therapeutic options for mucormycosis treatment have become available but none have shown promising results, and larger studies are required to assess their efficacy.
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spelling pubmed-57608742018-02-07 Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management Manjunath, M Prajapat, Deepak Sharma, Rahul Kumar Talwar, Deepak Lung India Case Report Pulmonary mucormycosis is a life-threatening opportunistic fungal infection. It is considered as a disease of immunocompromised state and is rarely seen in immunocompetent patients. We here report a case of refractory bronchovascular pleuropulmonary mucormycosis, who despite early detection, optimal management with liposomal amphotericin B, and posaconazole therapy followed by surgery, progressed further and led to a fatal outcome. Dual antifungal therapy combined with surgery is the only definitive treatment option available in the literature. Many new therapeutic options for mucormycosis treatment have become available but none have shown promising results, and larger studies are required to assess their efficacy. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5760874/ /pubmed/29319040 http://dx.doi.org/10.4103/lungindia.lungindia_535_16 Text en Copyright: © 2017 Indian Chest Society http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Manjunath, M
Prajapat, Deepak
Sharma, Rahul Kumar
Talwar, Deepak
Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management
title Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management
title_full Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management
title_fullStr Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management
title_full_unstemmed Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management
title_short Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management
title_sort refractory bronchovascular pleuropulmonary mucormycosis: case report and difficulties in management
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760874/
https://www.ncbi.nlm.nih.gov/pubmed/29319040
http://dx.doi.org/10.4103/lungindia.lungindia_535_16
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