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Preparation of gastro-resistant pellets containing chitosan microspheres for improvement of oral didanosine bioavailability
The purpose of this work was to introduce a new concept of coated pellets containing chitosan microspheres loaded with didadosine for oral administration, aiming at reducing the frequency of administration and improving the bioavailability by a suitable release profile. Chitosan microspheres were pr...
Autores principales: | Severino, Patrícia, de Oliveira, George G.G., Ferraz, Humberto G., Souto, Eliana B., Santana, Maria H.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760906/ https://www.ncbi.nlm.nih.gov/pubmed/29403741 http://dx.doi.org/10.1016/j.jpha.2012.02.005 |
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