Simultaneous quantification of prodrug oseltamivir and its metabolite oseltamivir carboxylate in human plasma by LC–MS/MS to support a bioequivalence study

A simple, precise and rapid liquid chromatography–tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the simultaneous determination of oseltamivir and oseltamivir carboxylate, a neuraminidase inhibitor, using their deuterated analogs as internal standards (ISs). The meth...

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Detalles Bibliográficos
Autores principales: Gupta, Ajay, Guttikar, Swati, Shrivastav, Pranav S., Sanyal, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760963/
https://www.ncbi.nlm.nih.gov/pubmed/29403810
http://dx.doi.org/10.1016/j.jpha.2012.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760963/
https://www.ncbi.nlm.nih.gov/pubmed/29403810
http://dx.doi.org/10.1016/j.jpha.2012.11.004

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