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Development and validation of a rapid chromatographic method for the analysis of flunarizine and its main production impurities
A rapid selective method for the analysis of flunarizine and its associated impurities was developed and validated according to ICH guidelines. The separation was carried out using a Thermo Scientific Hypersil Gold C18 column (50 mm×4.6 mm i.d., 1.9 μm particle size) with a gradient mobile phase of...
Autores principales: | O’Connor, Niamh, Geary, Michael, Wharton, Mary, Sweetman, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760976/ https://www.ncbi.nlm.nih.gov/pubmed/29403819 http://dx.doi.org/10.1016/j.jpha.2012.12.005 |
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