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Determination and stress studies on YK-1101, a potential histone deacetylase, by HPLC–UV and HPLC–TOF/MS methods

YK-1101, with its structure as S-((E)-4-((7S,10S,Z)-4-ethylidene-7-isopropyl-2,5,8,12-tetraoxo -9-oxa-16-thia-3,6,13,18-tetraazabicyclo[13.2.1]octadeca-1(17),15(18)-dien-10-yl)but-3-en-1-yl) ethanethioate, is synthesized as a potential histone deacetylase inhibitor. Its quality and stability under v...

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Detalles Bibliográficos
Autores principales: Zhou, Chen, Liu, Wen-Yuan, Feng, Feng, Ye, Hai, Wu, Chun-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760985/
https://www.ncbi.nlm.nih.gov/pubmed/29403812
http://dx.doi.org/10.1016/j.jpha.2013.01.003