Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography

A high-speed counter-current chromatography (HSCCC) method was successfully developed for the preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus in one step. The purity of deoxyschizandrin was 98.5%, and the structure was identified by MS, UV and NMR....

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Autores principales: Li, Xin-Ying, Yang, Mei, Huang, Jie-Yun, Yu, Xiao-Xue, Zhao, Min-Qian, Liang, Zhi-Kun, Xie, Zhi-Sheng, Xu, Xin-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761001/
https://www.ncbi.nlm.nih.gov/pubmed/29403850
http://dx.doi.org/10.1016/j.jpha.2013.07.002
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author Li, Xin-Ying
Yang, Mei
Huang, Jie-Yun
Yu, Xiao-Xue
Zhao, Min-Qian
Liang, Zhi-Kun
Xie, Zhi-Sheng
Xu, Xin-Jun
author_facet Li, Xin-Ying
Yang, Mei
Huang, Jie-Yun
Yu, Xiao-Xue
Zhao, Min-Qian
Liang, Zhi-Kun
Xie, Zhi-Sheng
Xu, Xin-Jun
author_sort Li, Xin-Ying
collection PubMed
description A high-speed counter-current chromatography (HSCCC) method was successfully developed for the preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus in one step. The purity of deoxyschizandrin was 98.5%, and the structure was identified by MS, UV and NMR. This method was simple, fast, convenient and appropriate to prepare pure compound as reference substances for related research on Schisandrae Sphenantherae Fructus.
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spelling pubmed-57610012018-02-05 Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography Li, Xin-Ying Yang, Mei Huang, Jie-Yun Yu, Xiao-Xue Zhao, Min-Qian Liang, Zhi-Kun Xie, Zhi-Sheng Xu, Xin-Jun J Pharm Anal Original Article A high-speed counter-current chromatography (HSCCC) method was successfully developed for the preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus in one step. The purity of deoxyschizandrin was 98.5%, and the structure was identified by MS, UV and NMR. This method was simple, fast, convenient and appropriate to prepare pure compound as reference substances for related research on Schisandrae Sphenantherae Fructus. Xi'an Jiaotong University 2013-12 2013-07-24 /pmc/articles/PMC5761001/ /pubmed/29403850 http://dx.doi.org/10.1016/j.jpha.2013.07.002 Text en © 2013 Xi’an Jiaotong University. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Original Article
Li, Xin-Ying
Yang, Mei
Huang, Jie-Yun
Yu, Xiao-Xue
Zhao, Min-Qian
Liang, Zhi-Kun
Xie, Zhi-Sheng
Xu, Xin-Jun
Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography
title Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography
title_full Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography
title_fullStr Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography
title_full_unstemmed Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography
title_short Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography
title_sort preparative separation and purification of deoxyschizandrin from schisandrae sphenantherae fructus by high-speed counter-current chromatography
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761001/
https://www.ncbi.nlm.nih.gov/pubmed/29403850
http://dx.doi.org/10.1016/j.jpha.2013.07.002
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