A validated LC–MS/MS method for the determination of tolterodine and its metabolite in rat plasma and application to pharmacokinetic study

Liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was used for simultaneous quantification of tolterodine and its metabolite 5-hydroxy methyl tolterodine in rat plasma. Tolterodine-d6 and 5-hydroxy methyl tolterodine-d14 were used as internal standards (IS). Chromatographic separation...

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Detalles Bibliográficos
Autores principales: Shaik, Rihana Parveen, Puttagunta, Srinivasa Babu, Kothapalli, Chandrasekhar Bannoth, Awen, Bahlul Zayed Sh., Challa, B.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761003/
https://www.ncbi.nlm.nih.gov/pubmed/29403860
http://dx.doi.org/10.1016/j.jpha.2013.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761003/
https://www.ncbi.nlm.nih.gov/pubmed/29403860
http://dx.doi.org/10.1016/j.jpha.2013.04.005

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