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Rapid sensitive validated UPLC–MS method for determination of venlafaxine and its metabolite in rat plasma: Application to pharmacokinetic study

A new ultra-performance liquid chromatography–electrospray ionization mass spectrometry (UPLC–MS/ESI) method for simultaneous determination of venlafaxine (VEN) and its metabolite O-desmethylvenlafaxine (ODV) in rat plasma has been developed and validated using Venlafaxine d6 as the internal standar...

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Detalles Bibliográficos
Autores principales:	Dubey, Sunil Kumar, Saha, R.N., Jangala, Hemanth, Pasha, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761014/ https://www.ncbi.nlm.nih.gov/pubmed/29403857 http://dx.doi.org/10.1016/j.jpha.2013.05.002

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