Voltammetric quantitation of nitazoxanide by glassy carbon electrode

The present study reports voltammetric reduction of nitazoxanide in Britton–Robinson (B–R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Rajeev, Kumar Yadav, Rajeev, Ahmad Rather, Jahangir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761018/
https://www.ncbi.nlm.nih.gov/pubmed/29403854
http://dx.doi.org/10.1016/j.jpha.2013.07.005
Descripción
Sumario:The present study reports voltammetric reduction of nitazoxanide in Britton–Robinson (B–R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20–140 µg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 μg/mL and 17.45 μg/mL, respectively.

Ejemplares similares