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Inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasiveness

BACKGROUND: The circadian clock is the basis for biological time keeping in eukaryotic organisms. The clock mechanism relies on biochemical signaling pathways to detect environmental stimuli and to regulate the expression of clock-controlled genes throughout the body. MAPK signaling pathways functio...

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Detalles Bibliográficos
Autores principales: Goldsmith, Charles S., Kim, Sam Moon, Karunarathna, Nirmala, Neuendorff, Nichole, Toussaint, L. Gerard, Earnest, David J., Bell-Pedersen, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761097/
https://www.ncbi.nlm.nih.gov/pubmed/29316898
http://dx.doi.org/10.1186/s12885-017-3896-y