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Direct detection and identification of active pharmaceutical ingredients in intact tablets by helium plasma ionization (HePI) mass spectrometry

A simple modification converts an electrospray ion source to an ambient-pressure helium plasma ionization source without the need of additional expensive hardware. Peaks for active ingredients were observed in the spectra recorded from intact pharmaceutical tablets placed in this source. A flow of h...

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Detalles Bibliográficos
Autores principales: Attygalle, Athula B., Jariwala, Freneil B., Pavlov, Julius, Yang, Zhihua, Mahr, Jason A., Oviedo, Mabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761121/
https://www.ncbi.nlm.nih.gov/pubmed/29403879
http://dx.doi.org/10.1016/j.jpha.2013.09.010