In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate

BACKGROUND: Technical limitations for culturing the human malaria parasite Plasmodium vivax have impaired the discovery of vaccine candidates, challenging the malaria eradication agenda. The immunogenicity of the M2 domain of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) antigen cloned...

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Detalles Bibliográficos
Autores principales: Cravo, Pedro, Machado, Renato B., Leite, Juliana A., Leda, Taizy, Suwanarusk, Rossarin, Bittencourt, Najara, Albrecht, Letusa, Judice, Carla, Lopes, Stefanie C. P., Lacerda, Marcus V. G., Ferreira, Marcelo U., Soares, Irene S., Goh, Yun Shan, Bargieri, Daniel Y., Nosten, François, Russell, Bruce, Rénia, Laurent, Costa, Fabio T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761135/
https://www.ncbi.nlm.nih.gov/pubmed/29316918
http://dx.doi.org/10.1186/s12936-017-2144-x

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