Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats

BACKGROUND: Chronic high-fat diet (HFD) consumption caused not only obese-insulin resistance, but also cognitive decline and microglial hyperactivity. Modified gut microbiota by prebiotics and probiotics improved obese-insulin resistance. However, the effects of prebiotics, probiotics, and synbiotic...

Descripción completa

Detalles Bibliográficos
Autores principales: Chunchai, Titikorn, Thunapong, Wannipa, Yasom, Sakawdaurn, Wanchai, Keerati, Eaimworawuthikul, Sathima, Metzler, Gabrielle, Lungkaphin, Anusorn, Pongchaidecha, Anchalee, Sirilun, Sasithorn, Chaiyasut, Chaiyavat, Pratchayasakul, Wasana, Thiennimitr, Parameth, Chattipakorn, Nipon, Chattipakorn, Siriporn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761137/
https://www.ncbi.nlm.nih.gov/pubmed/29316965
http://dx.doi.org/10.1186/s12974-018-1055-2

Ejemplares similares

Ejemplares similares