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CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) is one of the most common types of adult acute leukemia. Standard chemotherapies can induce complete remission in selected patients; however, a majority of patients eventually relapse and succumb to the disease. Thus, the development of novel therapeutics for...

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Detalles Bibliográficos
Autores principales: Wang, Jinghua, Chen, Siyu, Xiao, Wei, Li, Wende, Wang, Liang, Yang, Shuo, Wang, Weida, Xu, Liping, Liao, Shuangye, Liu, Wenjian, Wang, Yang, Liu, Nawei, Zhang, Jianeng, Xia, Xiaojun, Kang, Tiebang, Chen, Gong, Cai, Xiuyu, Yang, Han, Zhang, Xing, Lu, Yue, Zhou, Penghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761206/
https://www.ncbi.nlm.nih.gov/pubmed/29316944
http://dx.doi.org/10.1186/s13045-017-0553-5