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Simultaneous determination of borneol and its metabolite in rat plasma by GC–MS and its application to pharmacokinetic study

A gas chromatography mass spectrometry (GC–MS) method has been developed and fully validated for the simultaneous determination of natural borneol (NB) and its metabolite, camphor, in rat plasma. Following a single liquid–liquid extraction, the analytes were separated using an HP-5MS capillary colum...

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Detalles Bibliográficos
Autores principales: Sun, Xiu-Man, Liao, Qiong-Feng, Zhou, Yu-Ting, Deng, Xue-Jiao, Xie, Zhi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761216/
https://www.ncbi.nlm.nih.gov/pubmed/29403899
http://dx.doi.org/10.1016/j.jpha.2014.01.005