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Simultaneous determination of amlodipine, valsartan and hydrochlorothiazide by LC–ESI-MS/MS and its application to pharmacokinetics in rats

Polypill is a fixed-dose combination that contains three or more active ingredients used as a single daily pill to achieve a large effect in preventing cardiovascular disease with minimal adverse effects. A novel and accurate liquid chromatography tandem mass spectrometry method using electrospray i...

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Detalles Bibliográficos
Autores principales:	Gadepalli, Shankar Ganesh, Deme, Pragney, Kuncha, Madhusudana, Sistla, Ramakrishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2014
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761358/ https://www.ncbi.nlm.nih.gov/pubmed/29403906 http://dx.doi.org/10.1016/j.jpha.2013.12.003

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