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Direct injection HILIC–MS/MS analysis of darunavir in rat plasma applying supported liquid extraction

A novel bioanalytical method was developed and validated for the quantitative determination of darunavir (DRV) in rat plasma by employing hydrophilic interaction chromatography and tandem mass spectrometry (HILIC–MS/MS) with supported liquid extraction (SLE). Irbesartan (IRB) was used as an internal...

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Detalles Bibliográficos
Autores principales:	Ramesh, Bokka, Manjula, Nemali, Ramakrishna, Sistla, Devi, Potturi Sita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2015
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761474/ https://www.ncbi.nlm.nih.gov/pubmed/29403914 http://dx.doi.org/10.1016/j.jpha.2014.05.001

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