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Inhibition of IκBβ/NFκB signaling prevents LPS-induced IL1β expression without increasing apoptosis in the developing mouse lung

BACKGROUND: The pro-inflammatory consequences of IL1β expression contribute to the pathogenesis of BPD. Selectively targeting LPS-induced IκBβ/NFκB signaling attenuates IL1β mRNA expression in macrophages. Whether targeting IκBβ/NFκB signaling affects anti-apoptotic gene expression, a known conseque...

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Detalles Bibliográficos
Autores principales:	McKenna, Sarah, Butler, Brittany, Jatana, Laurie, Ghosh, Sankar, Wright, Clyde J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761659/ https://www.ncbi.nlm.nih.gov/pubmed/28753596 http://dx.doi.org/10.1038/pr.2017.182

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