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When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity

Treatment-resistant schizophrenia is a serious clinical problem. We adopt a systems-level approach positing a greater role for cognitive control mechanisms in the development of psychotic symptoms and illustrate the clinical application of this via a case report of treatment-resistant patients treat...

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Detalles Bibliográficos
Autores principales: Lowe, Penelope, Krivoy, Amir, Porffy, Lilla, Henriksdottir, Erna, Eromona, Whiskey, Shergill, Sukhwinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761908/
https://www.ncbi.nlm.nih.gov/pubmed/29344345
http://dx.doi.org/10.1177/2045125317737003
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author Lowe, Penelope
Krivoy, Amir
Porffy, Lilla
Henriksdottir, Erna
Eromona, Whiskey
Shergill, Sukhwinder S.
author_facet Lowe, Penelope
Krivoy, Amir
Porffy, Lilla
Henriksdottir, Erna
Eromona, Whiskey
Shergill, Sukhwinder S.
author_sort Lowe, Penelope
collection PubMed
description Treatment-resistant schizophrenia is a serious clinical problem. We adopt a systems-level approach positing a greater role for cognitive control mechanisms in the development of psychotic symptoms and illustrate the clinical application of this via a case report of treatment-resistant patients treated successfully with adjunct pro-cognitive serotonergic medication.
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spelling pubmed-57619082018-01-17 When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity Lowe, Penelope Krivoy, Amir Porffy, Lilla Henriksdottir, Erna Eromona, Whiskey Shergill, Sukhwinder S. Ther Adv Psychopharmacol Case Reports Treatment-resistant schizophrenia is a serious clinical problem. We adopt a systems-level approach positing a greater role for cognitive control mechanisms in the development of psychotic symptoms and illustrate the clinical application of this via a case report of treatment-resistant patients treated successfully with adjunct pro-cognitive serotonergic medication. SAGE Publications 2017-11-02 2018-01 /pmc/articles/PMC5761908/ /pubmed/29344345 http://dx.doi.org/10.1177/2045125317737003 Text en © The Author(s), 2017 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Reports
Lowe, Penelope
Krivoy, Amir
Porffy, Lilla
Henriksdottir, Erna
Eromona, Whiskey
Shergill, Sukhwinder S.
When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity
title When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity
title_full When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity
title_fullStr When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity
title_full_unstemmed When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity
title_short When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity
title_sort when the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761908/
https://www.ncbi.nlm.nih.gov/pubmed/29344345
http://dx.doi.org/10.1177/2045125317737003
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