Composite Biomarkers Derived from Micro-Electrode Array Measurements and Computer Simulations Improve the Classification of Drug-Induced Channel Block

The Micro-Electrode Array (MEA) device enables high-throughput electrophysiology measurements that are less labor-intensive than patch-clamp based techniques. Combined with human-induced pluripotent stem cells cardiomyocytes (hiPSC-CM), it represents a new and promising paradigm for automated and ac...

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Detalles Bibliográficos
Autores principales: Tixier, Eliott, Raphel, Fabien, Lombardi, Damiano, Gerbeau, Jean-Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762138/
https://www.ncbi.nlm.nih.gov/pubmed/29354067
http://dx.doi.org/10.3389/fphys.2017.01096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762138/
https://www.ncbi.nlm.nih.gov/pubmed/29354067
http://dx.doi.org/10.3389/fphys.2017.01096

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