A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice

Adaptive autoimmunity is restrained by controlling population sizes and pathogenicity of harmful clones, while innate destruction is controlled at effector phase. We report here that deletion of Rptor in mouse hematopoietic stem/progenitor cells causes self-destructive innate immunity by massively i...

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Detalles Bibliográficos
Autores principales: Tang, Fei, Zhang, Peng, Ye, Peiying, Lazarski, Christopher A, Wu, Qi, Bergin, Ingrid L, Bender, Timothy P, Hall, Michael N, Cui, Ya, Zhang, Liguo, Jiang, Taijiao, Liu, Yang, Zheng, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762159/
https://www.ncbi.nlm.nih.gov/pubmed/29206103
http://dx.doi.org/10.7554/eLife.32497

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