Altered GNAS imprinting due to folic acid deficiency contributes to poor embryo development and may lead to neural tube defects

Disturbed epigenetic modifications have been linked to the pathogenesis of Neural Tube Defects (NTDs) in those with folate deficiency during pregnancy. However, evidence is lacking to delineate the critical region in epigenome regulated by parental folic acid and mechanisms by which folate deficienc...

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Detalles Bibliográficos
Autores principales: Wang, Li, Chang, Shaoyan, Wang, Zhen, Wang, Shan, Huo, Junsheng, Ding, Gangqiang, Li, Rui, Liu, Chi, Shangguan, Shaofang, Lu, Xiaolin, Zhang, Ting, Qiu, Zhiyong, Wu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762285/
https://www.ncbi.nlm.nih.gov/pubmed/29340017
http://dx.doi.org/10.18632/oncotarget.22731

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