Cargando…
Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets
Defining the mutational landscape of classic Hodgkin lymphoma is still a major research goal. New targeted next-generation sequencing (NGS) techniques may identify pathogenic mechanisms and new therapeutic opportunities related to this disease. We describe the mutational profile of a series of 57 cH...
Autores principales: | Mata, Elena, Díaz-López, Antonio, Martín-Moreno, Ana M., Sánchez-Beato, Margarita, Varela, Ignacio, Mestre, María J., Santonja, Carlos, Burgos, Fernando, Menárguez, Javier, Estévez, Mónica, Provencio, Mariano, Sánchez-Espiridión, Beatriz, Díaz, Eva, Montalbán, Carlos, Piris, Miguel A., García, Juan F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762329/ https://www.ncbi.nlm.nih.gov/pubmed/29340061 http://dx.doi.org/10.18632/oncotarget.22799 |
Ejemplares similares
-
Genomic analyses of microdissected Hodgkin and Reed-Sternberg cells: mutations in epigenetic regulators and p53 are frequent in refractory classic Hodgkin lymphoma
por: Mata, Elena, et al.
Publicado: (2019) -
HLA Allele E*01:01 Is Associated with a Reduced Risk of EBV-Related Classical Hodgkin Lymphoma Independently of HLA-A*01/*02
por: Martín, Paloma, et al.
Publicado: (2015) -
CSF1R Protein Expression in Reactive Lymphoid Tissues and Lymphoma: Its Relevance in Classical Hodgkin Lymphoma
por: Martín-Moreno, Ana M., et al.
Publicado: (2015) -
Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma
por: Gomez, Felicia, et al.
Publicado: (2023) -
Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols
por: Greaves, Wesley, et al.
Publicado: (2012)