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Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice

Cells universally adapt to ischemic conditions by turning on a transcription factor hypoxia-inducible factor (HIF), in which its role is known to differ widely across many different types of cells. Given that microglia have been reported as an essential mediator of neuroinflammation in many brain di...

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Detalles Bibliográficos
Autores principales: Bok, Seoyeon, Kim, Young-Eun, Woo, Youngsik, Kim, Soeun, Kang, Suk-Jo, Lee, Yoontae, Park, Sang Ki, Weissman, Irving L., Ahn, G-One
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762339/
https://www.ncbi.nlm.nih.gov/pubmed/29340071
http://dx.doi.org/10.18632/oncotarget.22851

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