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Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis
Deoxypodophyllotoxin (DPT) is a naturally occurring flavolignan isolated from Anthriscus sylvestris. Recently, it has been reported that DPT inhibits tubulin polymerization and induces G2/M cell cycle arrest followed by apoptosis through multiple cellular processes. Despite these findings, details r...
Autores principales: | Kim, Sang-Hun, Kim, Kwang-Youn, Park, Sul-Gi, Yu, Sun-Nyoung, Kim, Young-Wook, Nam, Hyo-Won, An, Hyun-Hee, Kim, Young-Woo, Ahn, Soon-Cheol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762344/ https://www.ncbi.nlm.nih.gov/pubmed/29340076 http://dx.doi.org/10.18632/oncotarget.22875 |
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