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CRISPR-Cas9 HDR system enhances AQP1 gene expression

Ionizing radiation (IR) isthe primarytherapeutic tool to treat patients with cancerous lesions located in the head and neck. In many patients, IR results in irreversible and severe salivary gland dysfunction or xerostomia. Currently there are no effective treatment options to reduce the effects of x...

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Detalles Bibliográficos
Autores principales: Wang, Zhimin, Wang, Yaohe, Wang, Songling, Zhang, Li-Rong, Zhang, Na, Cheng, Zhenguo, Liu, Qingshi, Shields, Kelly J., Hu, Baoli, Passineau, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762352/
https://www.ncbi.nlm.nih.gov/pubmed/29340084
http://dx.doi.org/10.18632/oncotarget.22901

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