Cargando…
Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway
Amino acid supplementation is an efficient and effective strategy to increase sperm quality. In our research, a comparative study was conducted to screen free amino acids to improve sperm motility, and we found that leucine was the most efficient one. Leucine treatment increases sperm motility depen...
Autores principales: | Zhang, Jin, Zhang, Xuemei, Liu, Yingjie, Su, Zihao, Dawar, Farman Ullah, Dan, Hong, He, Yan, Gui, Jian-Fang, Mei, Jie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762361/ https://www.ncbi.nlm.nih.gov/pubmed/29340093 http://dx.doi.org/10.18632/oncotarget.22910 |
Ejemplares similares
-
Acetylated microtubules are required for fusion of autophagosomes with lysosomes
por: Xie, Rui, et al.
Publicado: (2010) -
BORC coordinates encounter and fusion of lysosomes with autophagosomes
por: Jia, Rui, et al.
Publicado: (2017) -
AMPK contributes to autophagosome maturation and lysosomal fusion
por: Jang, Minsu, et al.
Publicado: (2018) -
Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome–autophagosome fusion
por: Mohan, Nitin, et al.
Publicado: (2019) -
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation
por: Zhan, Yunyan, et al.
Publicado: (2020)