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Hypermutation and microsatellite instability in gastrointestinal cancers

Recent progress in cancer genome analysis using next-generation sequencing has revealed a high mutation burden in some tumors. The particularly high rate of somatic mutation in these tumors correlates with the generation of neo-antigens capable of eliciting an immune response. Identification of hype...

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Detalles Bibliográficos
Autores principales:	Yuza, Kizuki, Nagahashi, Masayuki, Watanabe, Satoshi, Takabe, Kazuaki, Wakai, Toshifumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762383/ https://www.ncbi.nlm.nih.gov/pubmed/29340115 http://dx.doi.org/10.18632/oncotarget.22783

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