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Optimized high performance liquid chromatography–ultraviolet detection method using core-shell particles for the therapeutic monitoring of methotrexate()

Methotrexate (MTX) is an antineoplastic drug, and due to its high toxicity, the therapeutic drug monitoring is strictly conducted in the clinical practice. The chemometric optimization and validation of a high performance liquid chromatography (HPLC) method using core–shell particles is presented fo...

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Detalles Bibliográficos
Autores principales:	Montemurro, Milagros, De Zan, María M., Robles, Juan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762447/ https://www.ncbi.nlm.nih.gov/pubmed/29403969 http://dx.doi.org/10.1016/j.jpha.2015.12.001

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