Liquid chromatography–tandem mass spectrometry method for simultaneous determination of valproic acid and its ene-metabolites in epilepsy patient plasma()

A simple and high throughput method was developed and validated for simultaneous determination of valproic acid and its two toxicant ene-metabolites, 2-enevalproic acid and 4-enevalproic acid in epilepsy patient plasma using liquid chromatography–tandem mass spectrometry. Probenecid was used as inte...

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Detalles Bibliográficos
Autores principales: Lu, Huan, Su, Chong, Yin, Lei, Gu, Liqiang, Gu, Jingkai, Chen, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762450/
https://www.ncbi.nlm.nih.gov/pubmed/29403970
http://dx.doi.org/10.1016/j.jpha.2015.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762450/
https://www.ncbi.nlm.nih.gov/pubmed/29403970
http://dx.doi.org/10.1016/j.jpha.2015.11.006

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