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Liquid chromatography–tandem mass spectrometry method for simultaneous determination of valproic acid and its ene-metabolites in epilepsy patient plasma()
A simple and high throughput method was developed and validated for simultaneous determination of valproic acid and its two toxicant ene-metabolites, 2-enevalproic acid and 4-enevalproic acid in epilepsy patient plasma using liquid chromatography–tandem mass spectrometry. Probenecid was used as inte...
Autores principales: | Lu, Huan, Su, Chong, Yin, Lei, Gu, Liqiang, Gu, Jingkai, Chen, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762450/ https://www.ncbi.nlm.nih.gov/pubmed/29403970 http://dx.doi.org/10.1016/j.jpha.2015.11.006 |
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