Development of an LC–MS/MS method for the quantitation of deoxyglycychloxazol in rat plasma and its application in pharmacokinetic study()

Deoxyglycychloxazol (TY501) is a glycyrrhetinic acid derivative which exhibits high anti-inflammatory activity and reduced pseudoaldosteronism compared to glycyrrhetinic acid. In this study, a sensitive and rapid liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was established for th...

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Detalles Bibliográficos
Autores principales: Li, Rongshan, Ran, Ruixue, Li, Quansheng, Huang, Yurong, Gu, Yuan, Si, Duanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762495/
https://www.ncbi.nlm.nih.gov/pubmed/29403980
http://dx.doi.org/10.1016/j.jpha.2016.03.002

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