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Lysosome-targeting agents in cancer therapy

Despite considerable efforts from multiple laboratories worldwide, highly specific inhibitors of autophagy for clinical use are not yet available. Lysosomal inhibitors are being employed instead, in spite of multiple limitations that are summarized herein.

Detalles Bibliográficos
Autores principales: Kroemer, Guido, Galluzzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762500/
https://www.ncbi.nlm.nih.gov/pubmed/29348815
http://dx.doi.org/10.18632/oncotarget.21451