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High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines

Hepatofibrosis, which leads to cirrhosis and eventual hepatocellular carcinoma, is a common response to chronic toxin-mediated liver injury. Nitrosamines are potent hepatotoxic agents that cause necrosis and subsequent fibrosis in the liver as a result of cytochrome P450 2E1 (CYP2E1)-dependent metab...

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Detalles Bibliográficos
Autores principales:	Gao, Jie, Wang, Gao-Ju, Wang, Zhao, Gao, Na, Li, Jing, Zhang, Yun-Fei, Zhou, Jun, Zhang, Hong-Xin, Wen, Qiang, Jin, Han, Qiao, Hai-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762503/ https://www.ncbi.nlm.nih.gov/pubmed/29348818 http://dx.doi.org/10.18632/oncotarget.22937

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