Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer

Pathogenic germline BRCA1, BRCA2 (BRCA1/2), and several other gene variants predispose women to primary ovarian, fallopian tube, and peritoneal carcinoma (OC), although variant frequency and relevance information is scarce in Japanese women with OC. Using targeted panel sequencing, we screened 230 u...

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Detalles Bibliográficos
Autores principales: Hirasawa, Akira, Imoto, Issei, Naruto, Takuya, Akahane, Tomoko, Yamagami, Wataru, Nomura, Hiroyuki, Masuda, Kiyoshi, Susumu, Nobuyuki, Tsuda, Hitoshi, Aoki, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762508/
https://www.ncbi.nlm.nih.gov/pubmed/29348823
http://dx.doi.org/10.18632/oncotarget.22733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762508/
https://www.ncbi.nlm.nih.gov/pubmed/29348823
http://dx.doi.org/10.18632/oncotarget.22733

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