K(Ca)3.1 channel inhibition leads to an ICAM-1 dependent increase of cell-cell adhesion between A549 lung cancer and HMEC-1 endothelial cells

Early metastasis leads to poor prognosis of lung cancer patients, whose 5-year survival rate is only 15%. We could recently show that the Ca(2+) sensitive K(+) channel K(Ca)3.1 promotes aggressive behavior of non-small cell lung cancer (NSCLC) cells and that it can serve as a prognostic marker in NS...

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Detalles Bibliográficos
Autores principales: Bulk, Etmar, Kramko, Nadzeya, Liashkovich, Ivan, Glaser, Felix, Schillers, Hermann, Schnittler, Hans-Joachim, Oberleithner, Hans, Schwab, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762509/
https://www.ncbi.nlm.nih.gov/pubmed/29348824
http://dx.doi.org/10.18632/oncotarget.22735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762509/
https://www.ncbi.nlm.nih.gov/pubmed/29348824
http://dx.doi.org/10.18632/oncotarget.22735

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