Cargando…
A novel anti-CD146 antibody specifically targets cancer cells by internalizing the molecule
CD146 is an adhesion molecule present on many tumors (melanoma, kidney, pancreas, breast, ...). In addition, it has been shown to be expressed on vascular endothelial and smooth muscle cells. Generating an antibody able to specifically recognize CD146 in cancer cells (designated as tumor CD146), but...
Autores principales: | Nollet, Marie, Stalin, Jimmy, Moyon, Anaïs, Traboulsi, Waël, Essaadi, Amel, Robert, Stéphane, Malissen, Nausicaa, Bachelier, Richard, Daniel, Laurent, Foucault-Bertaud, Alexandrine, Gaudy-Marqueste, Caroline, Lacroix, Romaric, Leroyer, Aurélie S, Guillet, Benjamin, Bardin, Nathalie, Dignat-George, Françoise, Blot-Chabaud, Marcel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762510/ https://www.ncbi.nlm.nih.gov/pubmed/29348825 http://dx.doi.org/10.18632/oncotarget.22736 |
Ejemplares similares
-
Stem cell properties of peripheral blood endothelial progenitors are stimulated by soluble CD146 via miR-21: potential use in autologous cell therapy
por: Essaadi, Amel, et al.
Publicado: (2018) -
CD146/sCD146 in the Pathogenesis and Monitoring of Angiogenic and Inflammatory Diseases
por: Heim, Xavier, et al.
Publicado: (2020) -
Role of CD146 (MCAM) in Physiological and Pathological Angiogenesis—Contribution of New Antibodies for Therapy
por: Joshkon, Ahmad, et al.
Publicado: (2020) -
Soluble CD146 as a Potential Target for Preventing Triple Negative Breast Cancer MDA-MB-231 Cell Growth and Dissemination
por: Sharma, Akshita, et al.
Publicado: (2022) -
Soluble CD146, a biomarker and a target for preventing resistance to anti-angiogenic therapy in glioblastoma
por: Joshkon, Ahmad, et al.
Publicado: (2022)