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Roflumilast restores cAMP/PKA/CREB signaling axis for FtMt-mediated tumor inhibition of ovarian cancer

The abrogation of cAMP generation by overexpression of PDE isoforms promotes the inflammatory pathology, and the PDE inhibitors have showed the potential anti-inflammation effects in clinical. However, the function of PDE inhibitors in cancer treatment remains unclear. We here investigated the role...

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Detalles Bibliográficos
Autores principales:	Gong, Shipeng, Chen, Yongning, Meng, Fanliang, Zhang, Yadi, Wu, Huan, Wu, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762514/ https://www.ncbi.nlm.nih.gov/pubmed/29348829 http://dx.doi.org/10.18632/oncotarget.22866

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