Distinct roles of TRAF6 and TAK1 in the regulation of adipocyte survival, thermogenesis program, and high-fat diet-induced obesity

Chronic low-grade inflammation, adipocyte hypertrophy, and glucose intolerance are common features of obesity and a risk factor for cancer. Tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is an adaptor protein that also possesses a non-conventional E3 ubiquitin ligase activity. In r...

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Detalles Bibliográficos
Autores principales: Gallot, Yann S., McMillan, Joseph D., Xiong, Guangyan, Bohnert, Kyle R., Straughn, Alex R., Hill, Bradford G., Kumar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762532/
https://www.ncbi.nlm.nih.gov/pubmed/29348847
http://dx.doi.org/10.18632/oncotarget.22575

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