Cargando…

Comprehensive analysis of mRNA-lncRNA co-expression profile revealing crucial role of imprinted gene cluster DLK1-MEG3 in chordoma

Chordoma is a rare bone tumor with high recurrence rate, but the mechanism of its development is unclear. Long non-coding RNAs(lncRNAs) are recently revealed to be regulators in a variety of biological processed by targeting on mRNA transcription. Their expression profile and function in chordoma ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Hao, Zhang, Kai, Lu, Jian, Wu, Guizhong, Yang, Huilin, Chen, Kangwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762536/ https://www.ncbi.nlm.nih.gov/pubmed/29348851 http://dx.doi.org/10.18632/oncotarget.22616

Ejemplares similares

Deregulated expression of the imprinted DLK1-DIO3 region in glioblastoma stemlike cells: tumor suppressor role of lncRNA MEG3
por: Buccarelli, Mariachiara, et al.
Publicado: (2020)

LncRNA-NONHSAT024778 promote the proliferation and invasion of chordoma cell by regulating miR-1290/Robo1 axis
por: Wang, Bin, et al.
Publicado: (2021)

LncRNA NONHSAT114552 Sponges miR-320d to Promote Proliferation and Invasion of Chordoma Through Upregulating NRP1
por: Zhang, Kai, et al.
Publicado: (2021)

LncRNA and mRNA expression profiles reveal the potential roles of lncRNA contributing to regulating dural penetration in clival chordoma
por: Bai, Jiwei, et al.
Publicado: (2020)

miR-1290 inhibits chordoma cell proliferation and invasion by targeting Robo1
por: Wang, Bin, et al.
Publicado: (2019)

Loss of Imprinting and Allelic Switching at the DLK1-MEG3 Locus in Human Hepatocellular Carcinoma
por: Anwar, Sumadi Lukman, et al.
Publicado: (2012)

The Long Non-Coding RNA (lncRNA) AGAP2-AS1 is Upregulated in Ovarian Carcinoma and Negatively Regulates lncRNA MEG3
por: Chen, Jingjing, et al.
Publicado: (2019)

LncRNA POU3F3 promotes melanoma cell proliferation by downregulating lncRNA MEG3
por: Liu, Yingnan, et al.
Publicado: (2021)

Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders
por: Abi Habib, Walid, et al.
Publicado: (2019)

LncRNA HLA-F-AS1 Enhances the Migration, Invasion and Apoptosis of Glioblastoma Cells by Targeting lncRNA MEG3
por: Wang, Yanhua, et al.
Publicado: (2021)

The Association of MEG3 lncRNA with Nuclear Speckles in Living Cells
por: Hasenson, Sarah E., et al.
Publicado: (2022)

A review on the role of MEG8 lncRNA in human disorders
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2022)

Comprehensive Analysis of the lncRNA–miRNA–mRNA Regulatory Network for Intramuscular Fat in Pigs
por: Zhao, Yanhui, et al.
Publicado: (2023)

Comprehensive analysis of the lncRNA-miRNA-mRNA regulatory network for bladder cancer
por: Huang, Minyu, et al.
Publicado: (2021)

Comprehensive analysis of an lncRNA-miRNA-mRNA competing endogenous RNA network in pulpitis
por: Lei, Fangcao, et al.
Publicado: (2019)

Silencing by the imprinted Airn macro lncRNA: Transcription is the answer
por: Santoro, Federica, et al.
Publicado: (2013)

Methylene blue relieves the development of osteoarthritis by upregulating lncRNA MEG3
por: Li, Xinyi, et al.
Publicado: (2018)

Hypermethylation of lncRNA MEG3 impairs chemosensitivity of breast cancer cells
por: Li, Hongchang, et al.
Publicado: (2020)

LncRNA MEG3: Potential stock for precision treatment of cardiovascular diseases
por: Li, Zining, et al.
Publicado: (2022)

Identification of lncRNA biomarkers in hepatocellular carcinoma by comprehensive analysis of the lncRNA-mediated ceRNA network
por: Ye, Dingde, et al.
Publicado: (2022)

Construction of lncRNA‐miRNA‐mRNA network based on ceRNA mechanism reveals the function of lncRNA in the pathogenesis of gout
por: Chen, Feng, et al.
Publicado: (2022)

Comprehensive analysis of lncRNA-mRNA co-expression patterns identifies immune-associated lncRNA biomarkers in ovarian cancer malignant progression
por: Guo, Qiuyan, et al.
Publicado: (2015)

Integrated analysis of lncRNA and mRNA transcriptomes reveals the potential regulatory role of lncRNA in kiwifruit ripening and softening
por: Chen, Yiting, et al.
Publicado: (2021)

Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis
por: Zhang, Xiaojuan, et al.
Publicado: (2021)

Comprehensive analysis of lncRNA-associated ceRNA network reveals the novel potential of lncRNA, miRNA and mRNA biomarkers in human rectosigmoid junction cancer
por: Zhang, Qianshi, et al.
Publicado: (2021)

LncRNA MEG3-TRPV1 signaling regulates chronic inflammatory pain in rats
por: Peng, Jing-Wei, et al.
Publicado: (2022)

lncRNA ZEB2-AS1 Aggravates Progression of Non-Small Cell Lung Carcinoma via Suppressing PTEN Level
por: Chen, Xiao, et al.
Publicado: (2019)

An Integrated Analysis of miRNA, lncRNA, and mRNA Expression Profiles
por: Guo, Li, et al.
Publicado: (2014)

Concomitant downregulation of the imprinted genes DLK1 and MEG3 at 14q32.2 by epigenetic mechanisms in urothelial carcinoma
por: Greife, Annemarie, et al.
Publicado: (2014)

Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort
por: Nye, Monica D., et al.
Publicado: (2016)

Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy
por: Pawar, Kamlesh, et al.
Publicado: (2016)

Associations between lncRNA MEG3 polymorphisms and neuroblastoma risk in Chinese children
por: Zhuo, Zhen-Jian, et al.
Publicado: (2018)

LncRNA Meg3 protects endothelial function by regulating the DNA damage response
por: Shihabudeen Haider Ali, Mohamed Sham, et al.
Publicado: (2019)

Association of LncRNA MEG3 polymorphisms with efficacy of neoadjuvant chemotherapy in breast cancer
por: Bayarmaa, Battseren, et al.
Publicado: (2019)

Clinical Value of lncRNA MEG3 in High-Grade Serous Ovarian Cancer
por: Buttarelli, Marianna, et al.
Publicado: (2020)

Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway
por: Uroda, Tina, et al.
Publicado: (2019)

Mechanism associated with aberrant lncRNA MEG3 expression in gestational diabetes mellitus
por: Zhang, Hailing
Publicado: (2019)

Integrated Dissection of lncRNA-miRNA-mRNA Pairs and Potential Regulatory Role of lncRNA PCAT19 in Lung Adenocarcinoma
por: Tang, Xiaomei, et al.
Publicado: (2022)

Comprehensive Analysis of the mRNA-lncRNA Co-expression Profile and ceRNA Networks Patterns in Chronic Hepatitis B
por: Chen, Wenbiao, et al.
Publicado: (2019)

Construction of chronic glomerulonephritis‑related lncRNA‑mRNA regulatory network and lncRNA‑miRNA‑mRNA ceRNA network by bioinformatics analysis
por: Zhuang, Xing-Xing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5om4li71h1hmkibaf65sp5ig78