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Validation of a liquid chromatographic method for the pharmaceutical quality control of products containing elacridar()

Many anticancer drugs have an impaired bioavailability and poor brain penetration because they are substrates to drug efflux pumps such as P-glycoprotein and Breast Cancer Resistance Protein. Elacridar is a strong inhibitor of these two drug efflux pumps and therefore has great potential to improve...

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Detalles Bibliográficos
Autores principales:	Sawicki, Emilia, Hillebrand, Michel J., Rosing, Hilde, Schellens, Jan H.M., Nuijen, Bastiaan, Beijnen, Jos H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762608/ https://www.ncbi.nlm.nih.gov/pubmed/29403992 http://dx.doi.org/10.1016/j.jpha.2016.04.005

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