Specific inhibition of acetylcholinesterase as an approach to decrease muscarinic side effects during myasthenia gravis treatment

Non-selective inhibitors of cholinesterases (ChEs) are clinically used for treatment of myasthenia gravis (MG). While being generally safe, they cause numerous adverse effects including induction of hyperactivity of urinary bladder and intestines affecting quality of patients life. In this study we...

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Detalles Bibliográficos
Autores principales: Petrov, Konstantin A., Kharlamova, Alexandra D., Lenina, Oksana A., Nurtdinov, Ayrat R., Sitdykova, Marina E., Ilyin, Victor I., Zueva, Irina V., Nikolsky, Evgeny E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762639/
https://www.ncbi.nlm.nih.gov/pubmed/29321572
http://dx.doi.org/10.1038/s41598-017-18307-9

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