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CRISPR/Cas9-mediated gene modification and gene knock out in the human-infective parasite Trichomonas vaginalis

The sexually-transmitted parasite Trichomonas vaginalis infects ~1/4 billion people worldwide. Despite its prevalence and myriad adverse outcomes of infection, the mechanisms underlying T. vaginalis pathogenesis are poorly understood. Genetic manipulation of this single-celled eukaryote has been hin...

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Detalles Bibliográficos
Autores principales:	Janssen, Brian D., Chen, Yi-Pei, Molgora, Brenda M., Wang, Shuqi E., Simoes-Barbosa, Augusto, Johnson, Patricia J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762654/ https://www.ncbi.nlm.nih.gov/pubmed/29321601 http://dx.doi.org/10.1038/s41598-017-18442-3

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