COX-2 induces oncogenic micro RNA miR655 in human breast cancer

We show that Cyclooxygenase-2 over-expression induces an oncogenic microRNA miR655 in human breast cancer cells by activation of EP4. MiR655 expression positively correlated with COX-2 in genetically disparate breast cancer cell lines and increased in all cell lines when grown as spheroids, implicat...

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Detalles Bibliográficos
Autores principales: Majumder, Mousumi, Dunn, Leanna, Liu, Ling, Hasan, Asma, Vincent, Krista, Brackstone, Muriel, Hess, David, Lala, Peeyush K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762661/
https://www.ncbi.nlm.nih.gov/pubmed/29321644
http://dx.doi.org/10.1038/s41598-017-18612-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762661/
https://www.ncbi.nlm.nih.gov/pubmed/29321644
http://dx.doi.org/10.1038/s41598-017-18612-3

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