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Tumor suppressor activity of miR-451: Identification of CARF as a new target

microRNAs (miRs) have recently emerged as small non-coding regulators of gene expression. We performed a loss-of-function screening by recruiting retrovirus mediated arbitrary manipulation of genome coupled with escape of cells from 5-Aza-2′-deoxycytidine (5-Aza-dC)-induced senescence. miRNA pool fr...

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Detalles Bibliográficos
Autores principales: Li, Ling, Gao, Ran, Yu, Yue, Kaul, Zeenia, Wang, Jia, Kalra, Rajkumar S., Zhang, Zhenya, Kaul, Sunil C., Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762681/
https://www.ncbi.nlm.nih.gov/pubmed/29321561
http://dx.doi.org/10.1038/s41598-017-18559-5

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